[14] Penarol 1-0 Nacional De Football [9] 2022-02-27 20:00
Stadium: Estadio Campeon del Siglo Round: 4
Referee: Leodan Frankin Gonzalez Cabrera Home Manager: Mauricio Larriera Away Manager: Pablo Repetto
Head to Head
| Europa - Towarzyskie | 2022/01/26 22:00 | Penarol v Nacional De Football | W | 1-0 |
| Urugwaj - Clausura | 2021/10/31 19:00 | Penarol v Nacional De Football | D | 0-0 |
| Copa Sudamericana | 2021/07/23 00:30 | Penarol v Nacional De Football | L | 0-1 |
| Copa Sudamericana | 2021/07/16 00:30 | Nacional De Football v Penarol | W | 1-2 |
| Urugwaj - Apertura | 2021/07/04 19:00 | Nacional De Football v Penarol | L | 2-0 |
| Urugwaj - Clausura | 2021/02/03 21:30 | Penarol v Nacional De Football | D | 0-0 |
| Urugwaj - Torneo Intermedio | 2020/12/13 20:30 | Penarol v Nacional De Football | W | 3-2 |
| Urugwaj - Apertura | 2020/08/09 18:00 | Nacional De Football v Penarol | D | 1-1 |
Home History
| Urugwaj - Apertura | 2022/02/19 23:00 | Albion FC v Penarol | D | 1-1 |
| Urugwaj - Apertura | 2022/02/13 23:00 | Penarol v Defensor Sporting | L | 0-1 |
| Urugwaj - Apertura | 2022/02/05 20:00 | Atletico Fenix Montevideo v Penarol | L | 1-0 |
| Urugwaj - Supercopa | 2022/01/30 22:00 | Plaza Colonia v Penarol | W | 0-1 |
| Europa - Towarzyskie | 2022/01/26 22:00 | Penarol v Nacional De Football | W | 1-0 |
| Ameryka - Towarzyskie | 2022/01/25 00:30 | Penarol v Santiago Wanderers | W | 2-0 |
| Ameryka - Towarzyskie | 2022/01/20 00:30 | Penarol v Nublense | W | 1-0 |
| Europa - Towarzyskie | 2022/01/17 22:15 | Penarol v Barracas Central | W | 4-0 |
Away History
| Urugwaj - Apertura | 2022/02/21 23:15 | Nacional De Football v Liverpool Montevideo | D | 0-0 |
| Urugwaj - Apertura | 2022/02/12 23:00 | Rentistas v Nacional De Football | W | 0-4 |
| Urugwaj - Apertura | 2022/02/06 23:00 | Nacional De Football v Deportivo Maldonado | L | 2-3 |
| Ameryka - Towarzyskie | 2022/01/30 00:30 | Nacional De Football v San Lorenzo | D | 2-2 |
| Europa - Towarzyskie | 2022/01/26 22:00 | Penarol v Nacional De Football | L | 1-0 |
| Europa - Towarzyskie | 2022/01/24 22:15 | Nacional De Football v Sarmiento | W | 1-0 |
| Europa - Towarzyskie | 2022/01/19 22:15 | Nacional De Football v Barracas Central | L | 1-2 |
| Europa - Towarzyskie | 2022/01/18 00:30 | Nacional De Football v Nublense | W | 6-4 |